Jean-Marc Crowet

Bioinformatics, modelling, biophysics

Articles in peer-reviewed journals (30)
Membrane remodelling mediates lipopeptide-induced immunity in Arabidopsis
Gilliard G., Prsic J., Crowet J.M., Chemotti C., Ahmed J., Lorent J., Jolivet M.D., Egli S., Egee S., Bouyer G., Race G., van Buren L., Van Den Berghe A., Arguelles-Arias A., Mathelie-Guinlet M., Ibrahim H., Genva M., Fouillen L., Mirande-Bret C., Razin O., Vue B., Zupunski M., Luzuriaga-Loaiza W.P., Deboever E., Nasir M.N., Lins L., Van Der Smissen P., Boubsi F., Eschrig S., Germain V., Hofte M., Zipfel C., Dufrene Y.F., Tyteca D., Koutsioubas A., Brocca P., Grossman G., Ranf S., Dorey S., De Coninck B., Nurnberger T., Mongrand S., Gronnier J., Rondelli V., Deleu M., Ongena M.
Nat. Plants. 2026  DOI: 10.1038/s41477-026-02270-3
Investigating the impact of active PHBV films on the nutritional quality of minimally processed apples
Khan M.R., Crowet J.M., Fadlallah S., Volpe S., Belloy N., Allais F., Gallos A., Torrieri E.
LWT. 2024  DOI: 10.1016/j.lwt.2024.116835
Dy-SheHeRASADe: A representation of the beta sheet dynamics through surface descriptors
Belghit H., Dauchez M., Crowet J.M., Jonquet-Prevoteau J.
J Mol Graph Model. 2024  DOI: 10.1016/j.jmgm.2024.108876
Challenging level of rigid-body approach involving numerical elements (CHLORAINE) applied to repeated elastin peptides
Depenveiller C., Wong H., Crowet J.M., Debelle L., Baud S., Dauchez M., Belloy N.
J Struct Biol. 2023  DOI: 10.1016/j.jsb.2023.107986
Multiscale modelling of the extracellular matrix
Wong H., Crowet J.M., Dauchez M., Ricard-Blum S., Baud S., Belloy N.
Matrix Biol Plus. 2021  DOI: 10.1016/j.mbplus.2021.100096
Sitosterol and glucosylceramide cooperative transversal and lateral uneven distribution in plant membranes
Rondelli V., Koutsioubas A., Prsic J., Deboever E., Crowet J.M., Lins L., Deleu M.
Sci Rep. 2021  DOI: 10.1038/s41598-021-00696-7
The Trypanosoma Brucei KIFC1 Kinesin Ensures the Fast Antibody Clearance Required for Parasite Infectivity
Lecordier L., Uzureau S., Vanwalleghem G., Deleu M., Crowet J.M., Barry P., Moran B., Voorheis P., Dumitru A.C., Yamaryo-Botté Y., Dieu M., Tebabi P., Vanhollebeke B., Lins L., Botté C.Y., Alsteens D., Dufrêne Y., Pérez-Morga D., Nolan D.P., Pays E.
iScience. 2020  DOI: 10.1016/j.isci.2020.101476
Structural Analysis of Nonapeptides Derived from Elastin
Hernández B., Crowet J.M., Thiery J., Kruglik S.G., Belloy N., Baud S., Dauchez M., Debelle L.
Biophys J. 2020  DOI: 10.1016/j.bpj.2020.04.019
Molecular Model for the Self-Assembly of the Cyclic Lipodepsipeptide Pseudodesmin A
Crowet J.M., Sinnaeve D., Fehér K., Laurin Y., Deleu M., Martins J.C., Lins L.
J Phys Chem B. 2019  DOI: 10.1021/acs.jpcb.9b08035
Multiple C2 domains and transmembrane region proteins (MCTPs) tether membranes at plasmodesmata
Brault M.L., Petit JD., Immel F., Nicolas W.J., Glavier M., Brocard L., Gaston A., Fouché M., Hawkins T.J., Crowet J.M., Grison M.S., Germain V., Rocher M., Kraner M., Alva V., Claverol S., Paterlini A., Helariutta Y., Deleu M., Lins L., Tilsner J., Bayer E.M.
EMBO Rep. 2019  DOI: 10.15252/embr.201847182
Low-diluted Phenacetinum disrupted the melanoma cancer cell migration
Fuselier C., Terryn C., Berquand A., Crowet J.M., Bonnomet A., Molinari M., Dauchez M., Martiny L., Schneider C.
Sci Rep.. 2019  DOI: 10.1038/s41598-019-45578-1
Linoleic and linolenic acid hydroperoxides interact differentially with biomimetic plant membranes in a lipid specific manner
Deleu M., Deboever E., Nasir M.N., Crowet J.M., Dauchez M., Ongena M., Jijakli H., Fauconnier ML., Lins L.
Colloids Surf B Biointerfaces. 2019  DOI: 10.1016/j.colsurfb.2018.12.014
Homology modeling and in vivo functional characterization of the zinc permeation pathway in a heavy metal P-type ATPase
Lekeux G., Crowet J.M.,* Nouet C., Joris M., Jadoul A., Bosman B., Carnol M., Motte P., Lins L., Galleni M., Hanikenne M.
J Exp Bot. 2019  DOI: 10.1093/jxb/ery353
Insight into the Self-Assembling Properties of Peptergents: A Molecular Dynamics Simulation Study
Crowet J.M., Nasir M.N., Dony N., Deschamps A., Stroobant V., Morsomme P., Deleu M., Soumillion P., Lins L
Int J Mol Sci. 2018  DOI: 10.3390/ijms19092772
Interaction between the barley allelochemical compounds gramine and hordenine and artificial lipid bilayers mimicking the plant plasma membrane
Lebecque S., Crowet JM., Lins L., Delory B.M., du Jardin P., Fauconnier M.L., Deleu M.
Sci Rep. 2018  DOI: 10.1038/s41598-018-28040-6
Differential Interaction of Synthetic Glycolipids with Biomimetic Plasma Membrane Lipids Correlates with the Plant Biological Response
Nasir M.N., Lins L., Crowet J.M., Ongena M., Dorey S., Dhondt-Cordelier S., Clément C., Bouquillon S., Haudrechy A., Sarazin C., Fauconnier M.L., Nott K., Deleu M.
Langmuir. 2017  DOI: 10.1021/acs.langmuir.7b01264
Molecular dynamics study of micelles properties according to their size
Lebecque S., Crowet J.M.,* Nasir M.N., Deleu M., Lins L.
J Mol Graph Model. 2017  DOI: 10.1016/j.jmgm.2016.12.007
Structural basis for plant plasma membrane protein dynamics and organization into functional nanodomains
Gronnier J., Crowet J.M., Habenstein B., Nasir M.N., Bayle V., Hosy E., Platre M.P., Gouguet P., Raffaele S., Martinez D., Grelard A., Loquet A., Simon-Plas F., Gerbeau-Pissot P., Der C., Bayer E.M., Jaillais Y., Deleu M., Germain V., Lins L., Mongrand S.
Elife. 2017  DOI: 10.7554/eLife.26404
Membrane Interactions of Natural Cyclic Lipodepsipeptides of the Viscosin Group
Geudens N., Nasir M.N., Crowet J.M., Raaijmakers J.M., Fehér K., Coenye T., Martins J.C., Lins L., Sinnaeve D., Deleu M.
Biochim Biophys Acta. 2017  DOI: 10.1016/j.bbamem.2016.12.013
Interactions of sugar-based bolaamphiphiles with biomimetic systems of plasma membranes
Nasir M.N., Crowet J.M., Lins L., Obounou Akong F., Haudrechy A., Bouquillon S., Deleu M.
Biochimie. 2016  DOI: 10.1016/j.biochi.2016.04.001
Complementary biophysical tools to investigate lipid specificity in the interaction between bioactive molecules and the plasma membrane: A review
Deleu M., Crowet J.M., Nasir M.N., Lins L.
Biochimica et Biophysica Acta – Biomembranes. 2014  DOI: 10.1016/j.bbamem.2014.08.023
Mechanism of Trypanosoma brucei gambiense resistance to human serum
Uzureau P., Uzureau S., Lecordier L., Fontaine F., Tebabi P., Homble F., Grelard A., Zhendre V., Nolan D.P., Lins L., Crowet J.M., Pays A., Felu C., Poelvoorde P., Vanhollebeke B., Moestrup S.K., Lyngso J., Pedersen J.S., Mottram J.C., Dufourc E. J., Perez-Morga D., Pays E.
Nature. 2013  DOI: 10.1038/nature12516
SAHBNET, an Accessible Surface-Based Elastic Network: An Application to Membrane Protein
Dony N., Crowet J.M.,* Joris B., Brasseur R., Lins L.
International Journal of Molecular Sciences. 2013  DOI: 10.3390/ijms140611510
Modeling of non-covalent complexes of the cell-penetrating peptide CADY and its siRNA cargo
Crowet J.M., Lins L., Deshayes S., Divita G., Morris M., Brasseur R., Thomas A.
Biochimica et Biophysica Acta. 2012  DOI: 10.1016/j.bbamem.2012.09.006
Plasma membrane localization of StREM1.3 Remorin is mediated by conformational changes in a novel C-terminal anchor and required for the restriction of PVX movement
Perraki A., Cacas J.L., Crowet J.M., Lins L., Castroviejo M., German-Retana S., Mongrand S., Raffaele S.
Plant Physiology. 2012  DOI: 10.1104/pp.112.200519
Multi-Scale Simulation of the Simian Immunodeficiency Virus Fusion Peptide
Crowet J.M., Parton D.L., Hall B.A., Steinhauer S., Brasseur R., Lins L., Sansom M.S.P.
Journal of Physical Chemistry B. 2012  DOI: 10.1021/jp3027385
Study of Thermomyces lanuginosa lipase in presence of tributyrylglycerol and water
Santini S., Crowet J.M.,* Thomas A., Paquot M., Vandenbol M., Thonart P., Wathelet J.P., Blecker C., Lognay G., Brasseur R., Lins L., Charloteaux B.
Biophysical Journal. 2009  DOI: 10.1016/j.bpj.2009.03.040
Impacts of the Carbonyl Group Location of Ester Bond on Interfacial Properties of Sugar-Based Surfactants: Experimental and Computational Evidences
Razafindralambo H., Blecker C., Mezdour S., Deroanne C., Crowet J.M., Brasseur R., Lins L., Paquot M.
Journal of Physical Chemistry B. 2009  DOI: 10.1021/jp903187f
Tilted properties of the 67-78 fragment of alpha-synuclein are responsible for membrane destabilization and neurotoxicity
Crowet J.M., Lins L., Dupiereux I., Elmoualija B., Lorin A., Charloteaux B., Stroobant V., Heinen E., Brasseur R.
Proteins. 2007  DOI: 10.1002/prot.21483
The N-terminal 12 residue long peptide of HIV gp41 is the minimal peptide sufficient to induce significant T-cell-like membrane destabilization in vitro
Charloteaux B., Lorin A., Crowet J.M., Stroobant V., Lins L., Thomas A., Brasseur R.
Journal of Molecular Biology. 2006  DOI: 10.1016/j.jmb.2006.04.018
Conference proceedings (2)
How do glycan and glycosaminoglycan composition influence protein dynamics? An example of small leucine-rich proteoglycans
Rao R., Gueroult M., Belloy N., Crowet J.M., Brezillon S., Dauchez M., Baud S.
European Biophysics Journal. (2021)  DOI: 10.1007/s00249-021-01558-w
13th European Biophysical Societies' Association Congress ( July 24-28, 2021 — Vienna, Austria)
Modeling of non-covalent complexes of the cell-penetrating peptide CADY and its siRNA cargo
Crowet J.M., Lins L., Deshayes S., Divita G., Morris M., Brasseur R., Thomas A.
European Biophysics Journal. (2013)  DOI: 10.1007/s00249-013-0917-x
9th EBSA European Biophysics Congress ( July 13-17, 2013 — Lisbon, Portugal)
Talks (33)
DURABIN: Multiscale modeling of Biological Systems
Youth Day de l'UMR CNRS/URCA 7369 MEDyC ( 2026 - Reims, France)
Molecular modelling, virtual reality and AI: real assets for observing, understanding and deciphering the multi-scale interactions of the ECM
Congres national annuel de la SFBMEC ( September 22-23, 2025 - Toulouse, France)
Simulating the Extra Cellular Matrix. From isolated elements to a reconstructed picture: key role of the in silico approach in understanding the influence of carbohydrate composition on protein dynamics
GlycoMADNESS Symposium ( September 4, 2025 - Paris, France)
Simulation of membrane protein interactions and lipid diversity
Workshop analyse in silico IIS Digibiocontrol X TRAIL ( June 25, 2025 - Gembloux, Belgium)
Modelisation et imagerie multi-echelles de la MEC
41emes Journees Scientifiques de l'AFERO ( January 16-17, 2025 - Reims, France)
Domain 36 of tropoelastin interacts with model membranes
Colloque des Utilisateurs de SOLEIL (SUM2025) ( 2025 - Gif-sur-Yvette, France)
Interactions des peptides d'elastine avec les membranes lipidiques : apport des simulations et de methodes biophysiques
Journee Romeo 2025 ( 2025 - Reims, France)
Exploring the interactions of elastin peptides with model membranes by numerical simulations
Journee des doctorants de MEDyC ( 2025 - Reims, France)
Exploring the interactions of elastin peptides with model membranes by numerical simulations
Journee des doctorants de l'ICMR ( 2025 - Reims, France)
Modeling and simulations of the extracellular matrix in a multiscale level
7th International Conference on Analytical and Nanoanalytical Methods for Biomedical and Environmental Sciences ( September 17-20, 2024 - Brasov, Romania)
Exploring the interactions of elastin peptides with model membranes by numerical simulations
Journee Romeo 2024 ( 2024 - Reims, France)
Domain 36 of tropoelastin interacts with model membranes
Journee Remoise des Jeunes Chercheurs en Sante 2024 ( 2024 - Reims, France)
Domain 36 of tropoelastin interacts with model membranes
Elastin2024 ( 2024 - Reims, France)
Simulation of membrane protein interactions and lipid diversity
4th Symposium on Current Trends in Membrane Protein Biophysics ( December 8, 2023 - Namur, Belgium)
Exploring the interactions of elastin peptides with model membranes by numerical simulations
Latinorum Investigatorum de Arteriis Colloquium (LIAC) ( 2023 - Barcelona, Spain)
The molecular properties of a biosourced molecule. A molecular modeling study
JCAD 2023 ( 2023 - Reims, France)
Molecular dynamics simulations of the extracellular matrix macromolecules as dynamic chains of rigid bodies
Journee Remoise des Jeunes Chercheurs en Sante ( October 21, 2021 - Reims, France)
Modeliser la matrice extracellulaire : que peuvent apporter les jeux videos pour mieux comprendre son fonctionnement ?
Seminaire Ecole doctorale Sciences Fondamentales et Sante ( June 3, 2021 - Reims, France)
Apport de la modelisation moleculaire et des simulations numeriques dans la comprehension des mecanismes d'actions de molecules biologiques
2eme WinterSchool AEBB ( February 8-10, 2021 - Reims, France (virtual))
Molecular Modeling of the extracellular components: from molecules to biomaterials?
Laboratory of Molecular Surfaces and Nanotechnology Seminar ( February 20, 2020 - Catania, Italy)
Interaction entre Rémorine et membrane plasmique végétale et simulation des membranes lipidiques complexes
Journée scientifique du centre de calcul régional ROMEO 2019 ( June 6, 2019 - Reims, France)
LBMI an approach for membranes
International Workshop on the asymetry of biological membranes ( April 29, 2016 - Besançon, France)
Simulation par dynamique moléculaire de membranes lipidiques complexes
MEDyC seminar ( November 25, 2015 - Reims, France)
Modeling of the cyclic lipodepsipeptide Pseudodesmin A self-assembly through molecular dynamic simulations
DutchBiophysics 2014 ( September 29-30, 2014 - Veldhoven, Netherlands)
Modeling of the cyclic lipodepsipeptide Pseudodesmin A self-assembly through molecular dynamic simulations
Gordon Research Conference - Computational Chemistry ( July 19-25, 2014 - West Dover, VT, USA)
Molecular dynamic simulation of the cyclic lipodepsipeptide Pseudodesmin A self-assembly
2nd meeting of the Belgian Peptide Group ( February 10-11, 2014 - Ghent, Belgium)
SAHBNET, An Accessible Surface-Based Elastic Network to Insert a Protein in a Complex Lipid Membrane
16 GEM and 10th GERLI meeting ( November 11, 2013 - Saint-Jean-Cap-Ferrat, France)
Simulations of a beta amphiphilic peptide as potential surfactant of membrane proteins
NSBM meeting 2013 ( October 25, 2013 - Maastricht, Netherlands)
Molecular dynamic simulations of a beta amphiphilic peptide
IAP 7/44 meeting ( October 3, 2013 - Liège, Belgium)
Multi-scale simulations of membrane active peptides: The fusion peptides
SBCB seminar ( May 19, 2010 - Oxford, United Kingdom)
Détection et caractérisation de peptides obliques au sein des protéines amyloïdogéniques
Laboratoire Interdisciplinaire Carnot de Bourgogne seminar ( March 12, 2010 - Dijon, France)
PepLook Scale-Up: Prediction of protein structures
IAP 6/19 meeting ( January 27, 2009 - Liège, Belgium)
Implication des peptides obliques dans la transconformation de protéines natives
5ème Conférence du Groupe de Contact de Biologie Structurale du FNRS ( September 12, 2003 - Liège, Belgium)
Posters (32)
DIMSuM - Dynamic Interactive Mesoscopics Simulations of the Membrane
Youth Day de l'UMR CNRS/URCA 7369 MEDyC ( 2026 - Reims, France)
DURABIN: Multiscale modeling of Biological Systems
Premiere journee des doctorants de l'UMR CNRS/URCA 7369 MEDyC 2025 ( 2025 - Reims, France)
DURABIN: Multiscale modeling of Biological Systems
Journee remoise des Jeunes Chercheurs en Sante 2025 ( 2025 - Reims, France)
Exploring the interations of elastin peptides with model membranes by numerical simulations
GEM2025 ( 2025 - Boulogne-sur-Mer, France)
DURABIN: Multiscale modeling of Biological Systems
5th Current Trends in Membrane Protein Biophysics ( 2025 - Namur, Belgium)
Exploring the interations of elastin peptides with model membranes by numerical simulations
Elastin2024 ( 2024 - Reims, France)
Exploring the interactions of elastin peptides with model membranes by numerical simulations
Journee remoise des Jeunes Chercheurs en Sante 2023 ( 2023 - Reims, France)
The molecular properties of a biosourced molecule. A molecular modeling study
JCAD 2023 ( 2023 - Reims, France)
Simulating large extracellular matrix molecules as dynamic chains of rigid bodies
22eme GGMM et 10eme rencontre de la Societe Francaise de Chemoinformatique ( September 29-October 1, 2021 - Lille, France)
LIMONADA : A database dedicated to the simulation of complex lipid membranes
22eme congres du GGMM ( September 29-October 1, 2021 - Lille, France)
Role of protein-sugar interactions in maintenance of protein dynamics and function in small leucine-rich proteoglycans
65th Biophysical Society Annual Meeting ( February 22-26, 2021 - Virtual conference)
LIMONADA : A database dedicated to the simulation of complex lipid membranes
Current trends in membrane protein biophysics ( 2021 - Namur, Belgium)
Extension of a simulator using rigid bodies dedicated to extracellular matrix
Winter school on structural biology, Bioexcel ( November 30-December 4, 2020 - Virtual conference)
LIMONADA : A database dedicated to the simulation of complex lipid membranes
Joint Meeting Club Exondo & GEM. Membrane Biophysics of Exo-Endocytosis: from Model Systems to Cells ( April 3-6, 2019 - Mandelieu-la-Napoule, France)
Multiple C2 domains and transmembrane region proteins (MCTPs) tether membranes at plasmodesmata
Current trends in membrane protein biophysics ( December 1, 2017 - Namur, Belgium)
Comanche : A shared platform for a lipidic database and a builder of complex lipid membranes
Journée VISION des plateaux techniques Centre Image (CI) et de Modelisation Moleculaire Multiechelle (P3M) ( November 23, 2017 - Reims, France)
Comanche : A shared platform for a lipidic database and a builder of complex lipid membranes
19th GEM congress ( November 5-8, 2017 - Roscoff, France)
Comanche : A shared platform for a lipidic database and a builder of complex lipid membranes
20th GGMM congress ( May 9-11, 2017 - Reims, France)
Simulation par dynamique moléculaire de membranes lipidiques complexes
Journées SFR Condorcet 2016 ( July 5-6, 2016 - Gembloux, Belgium)
Modeling of the cyclic lipodepsipeptide Pseudodesmin A self-assembly through molecular dynamic simulations
Joint French/German Biophysical Societies Meeting ( April 11-14, 2016 - Bad Herrenalb, Germany)
Experimental and in silico approaches to study the interaction of Remorin with plant plasma membrane
11th GERLI lipidomics meeting ( Octobre 25-28, 2015 - Bischoffsheim, France)
Modeling of the cyclic lipodepsipeptide Pseudodesmin A self-assembly through molecular dynamic simulations
Gordon Research Conference - Computational Chemistry ( July 19-25, 2014 - West Dover, VT, USA)
Simulations of a beta amphiphilic peptide as potential surfactant of membrane proteins
19ème Symposium National sur les Sciences Biologiques Appliquées ( February 7, 2014 - Gembloux, Belgium)
Modeling of non-covalent complexes of the cell-penetrating peptide CADY and its siRNA cargo
9th EBSA congress ( July 13-17, 2013 - Lisbon, Portugal)
in silico study of antimicrobial cyclic peptides Sequence analysis, molecular modelling and multi-scale molecular dynamics
IAP 7/44 meeting ( February 26, 2013 - Liège, Belgium)
Replacing explicit water and lipids by implicit representation in molecular dynamics simulations
Faraday Discussion 161 : Lipid and Membranes Biophysics ( September 11-13, 2012 - London, United Kingdom)
PepLook Scale-Up Prediction of protein structures
IAP 6/19 meeting ( August 27, 2009 - Liège, Belgium)
Detection and characterization of tilted peptides in amyloid proteins
Conférence Jacques Monod ( April 25-29, 2009 - Aussois, France)
Peculiar hydrophobic properties of the 67-78 fragment of α-synuclein are responsible for membrane destabilization and neurotoxicity
8th Conférence Internationale AD/PD ( March 14-18, 2007 - Salzburg, Austria)
Peculiar hydrophobic properties of the 67-78 fragment of α-synuclein are responsible for membrane destabilization and neurotoxicity
Young Scientists Day de la 194ème Réunion de la Société Belge de Biochimie et de Biologie Moléculaire ( December 18, 2006 - Gembloux, Belgium)
The Presence and Potential Role of Tilted Peptides in Amyloidogenic Proteins
Peptide Membrane Interaction ( October 9-12, 2004 - Namur, Belgium)
Study of the potential role of tilted peptides in transconformation: Theoritical analysis of amyloidogenic proteins
4ème Conférence du Groupe de Contact FNRS de Biologie Structurale ( May 23, 2003 - Gembloux, Belgium)
Awards and alike

Our work has been selected for the cover of the Biophysical Journal (Volume 118, Issue 11) in 2020

Travel award to go to the Gordon Research Conference at West Dover, USA in 2014